Onfekafusp alfa
Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research.
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- CAS No.: 1957239-88-1
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
[scFv-heavy-kappa]-trimer
Onfekafusp alfa shows a greater anticancer activity than both mTNFα and TN11mTNFα[2].
Onfekafusp alfa shows a 5 to 6 times higher activity than equimolar amounts of recombinant mTNFα and of the fusion protein TN11mTNFα in cytotoxic assay on L-M mouse fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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[scFv-heavy-kappa]-trimer
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 1957239-88-1
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SMILES
[Onfekafusp alfa]
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Synonyms
L19TNF
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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