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Cat. No.: HY-N21614

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Phaeusmane F

Phaeusmane F is a eudesmane-type sesquiterpene that inhibits LPS (HY-D1056)-induced nitric oxide (NO) production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM. Phaeusmane F is found in the rhizomes of Curcuma phaeocaulis. Phaeusmane F can be used in research related to inflammatory responses.

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CAS No.: 1450839-78-7
화학식: C₁₅H₂₀O₅
분자량:280.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phaeusmane F Chemical Structure

CAS No.: 1450839-78-7

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

All NO Synthase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	4.8 μM	Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm. Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm.	ejoc.201402465

In Vitro

Innate ImmunityOxidative Stress

Innate Immunity

Oxidative Stress

Phaeusmane F (compound 6) (24 h; 1 μg/mL LPS stimulation) inhibits LPS-induced NO production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM, without exhibiting significant cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1450839-78-7
분자량 280.32
화학식 C₁₅H₂₀O₅
SMILES

C[C@]12[C@@]([C@](O)(CCC2=O)C)([H])CC([C@](C1)(O3)O)=C(C)C3=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Liu Y, et al. Eudesmane-Type Sesquiterpenes from Curcuma phaeocaulis and Their Inhibitory Activities on Nitric Oxide Production in RAW 264.7 Cells. Eur J Org Chem. 2014:5540-5548.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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