[Phe2]-TRH
[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 34783-35-2
- 화학식: C19H24N4O4
- 분자량:372.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
![[Phe2]-TRH Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p3962.gif "Click to View [Phe2]-TRH Chemical Structure")
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
[Phe2]-TRH has a lower affinity for the TRH receptor than TRH itself, and the substitution of azPro for Pro in the [Phe2, azPro3]-TRH analogue causes an approximately 200-fold further loss in affinity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 34783-35-2
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분자량 372.42
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화학식 C19H24N4O4
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Sequence Shortening
Glp-FP-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Eckle E, et al. Conformational properties of central nervous system active thyrotropin releasing hormone analogues: probing structure-activity relationships at the molecular level. J Med Chem. 1985 Jan;28(1):125-37. [Content Brief]
[2]. Zhang WJ, et al. Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues. J Am Chem Soc. 2003 Feb 5;125(5):1221-35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
[Phe2]-TRH Related Classifications
HY-P3962 Related Classifications
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