Phenaglycodol
Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 79-93-6
- 화학식: C11H15ClO2
- 분자량:214.69
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
Phenaglycodol (55-80 mg/kg, i.p., 1 time) has antiepileptic activity in mice[1].
Phenaglycodol (50-100 mg/kg, i.g., 1 time) has antiepileptic activity in monkey[1].
Phenaglycodol (130mg/kg, i.p., 1 time) lowers the concentration of Meprobamate in serum and brain[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Cat[1]
-
Dosage:20 mg/kg
-
Administration:Intraperitoneal Injection (i.p.)
-
Result:Showed that cat became quiet.
-
Animal Model:Monkey[1]
-
Dosage:50-100 mg/kg
-
Administration:Intragastric Gavage (i.g.)
-
Result:Showed that monkey became less aggressive or less fearful.
-
Animal Model:Mice[1]
-
Dosage:55-80 mg/kg
-
Administration:Intraperitoneal Injection (i.p.)
-
Result:Showed a reduction in spontaneous activity and sit quietly.
-
Animal Model:Female Rats(Sprague-Dawley, 170g)[2]
-
Dosage:130 mg/kg
-
Administration:Intraperitoneal Injection (i.p.)
-
Result:Showed that the decrease of Meprobamate concentration in the serum and brain of the pretrealed rats was more rapid than that in control rats.
Chemical Information
-
CAS No. 79-93-6
-
분자량 214.69
-
화학식 C11H15ClO2
-
SMILES
ClC1=CC=C(C(C)(C(C)(C)O)O)C=C1
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
-
Data Sheet (271 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31. [Content Brief]
[2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phenaglycodol Related Classifications
HY-105845 Related Classifications
Powered by Bioz