Polyvinylimidazole
Based on 1 Customer Validation
Polyvinylimidazole (Vimdemer) is an antibacterial polymer and membrane modifier. Polyvinylimidazole can form anticancer complexes with Cadmium chloride. Polyvinylimidazole disrupts bacterial membrane structures through electrostatic and hydrophobic interactions, inhibits bacterial adhesion and biofilm formation, thereby reducing membrane surface biofouling and enhancing the water flux recovery rate after fouling-cleaning cycles. Polyvinylimidazole exhibits broad-spectrum but selective antibacterial activity, inhibiting fungi and bacteria. Polyvinylimidazole can modify PVDF membranes, and the modified membranes inhibit bacteria in a concentration-dependent manner. Polyvinylimidazole can be used in research related to cancer, fungal and bacterial infections.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.0%
- CAS No.: 25232-42-2
- 화학식: (C5H6N2)x
-
보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
In Vitro
After loading with polyvinylimidazole (5-15% w/v; 107 CFU/mL bacteria; 3 h filtration; before and after cleaning), the live cell area of E. coli and S. aureus on the membrane surface after dynamic fouling decreases, while the dead cell area increases, with the M15 membrane showing the lowest residual live cell area[2].
Polyvinylimidazole (5-15% w/v; 3 h) modified membranes cause structural disruption of adhered E. coli and S. aureus[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Kloeckera apiculata, Candida albicans, Escherichia coli, Salmonella enteritidis and Staphylococcus aureus
-
Concentration:0.5, 1 and 2 mg/mL
-
Incubation Time:1, 12 and 24
h -
Result:Both types of yeast died completely in 1 mg/mL concentration of this compound during 12-24 h treatments.
Exhibited antimicrobial activity against Escherichia coli, Salmonella enteritidis and Staphylococcus aureus.
Weaker activity was shown againstAspergillius niger and Penicillium roqueforti.
Chemical Information
-
CAS No. 25232-42-2
-
Appearance Solid
-
화학식 (C5H6N2)x
-
Color White to light yellow
-
SMILES
CC(CC)N1C=NC=C1.[n]
-
Synonyms
Vimdemer
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
순도&문서
-
Data Sheet (288 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)