CD1c
CD1c is a group 1 CD1 isoform that presents microbial and self lipids to a diverse repertoire of CD1c-restricted T cells. Known antigenic ligands include mycobacterial phosphomycoketide and mannosyl-beta1-phosphomycoketide, and CD1c-restricted clones responding to malignantly transformed cells have been isolated, supporting a role in tumor immune surveillance. Among blood dendritic cells, CD1c (formerly BDCA-1) defines the classical CD1c+ myeloid dendritic cell subset, and it is also expressed on B cells and Langerhans cells. Recent work shows that endogenous lipids, including certain methyl-branched fatty acids, can serve as CD1c ligands. CD1c is therefore widely used together with CD141 and CD1a to stratify human dendritic cell subsets.
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CD1c Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
