IgG
Immunoglobulin G (IgG) is the predominant antibody class in human serum, forming the bulk of circulating immunoglobulin and providing the principal humoral defense against pathogens and toxins. Each IgG molecule is a heterotetramer of two heavy and two light chains whose Fc region engages Fc gamma receptors on immune cells and the C1q component of complement, thereby coupling antigen recognition to phagocytosis, antibody-dependent cellular cytotoxicity, and complement activation. IgG is the only antibody class that crosses the placenta via FcRn, conferring neonatal passive immunity, and its pH-dependent FcRn recycling underlies the long serum half-life exploited by therapeutic monoclonal antibodies and IVIG therapy.
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IgG Recombinant Proteins (11)
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- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
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