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Cat. No.: HY-123681

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R 57720

R 57720 is an antiepileptic agent that exhibits dose-dependent anticonvulsant activity across multiple postnatal rat age groups. R 57720 inhibits severe generalized tonic-clonic seizures induced by Pentylenetetrazol. R 57720 can be used for epilepsy research.

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CAS No.: 98164-11-5
화학식: C₁₁H₈Cl₄N₂
분자량:310.01

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

R 57720 Chemical Structure

CAS No.: 98164-11-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

R 57720 (5-20 mg/kg) exhibits dose-dependent anticonvulsant activity against metrazol-induced seizures in rats of all postnatal ages tested, with high doses preventing minimal seizure onset in young rats where metrazol alone does not induce such seizures^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 98164-11-5
분자량 310.01
화학식 C₁₁H₈Cl₄N₂
SMILES

Cl/C(C1=C(C=C(C=C1)Cl)Cl)=C\N2C=CN=C2.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pohl M, et al. Anti-metrazol action of R 57720 during postnatal development in rats. Physiol Bohemoslov. 1988;37(2):115-21.
[Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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