RO5192022
RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1043489-40-2
- 화학식: C9H8F2N2O
- 분자량:198.17
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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TAAR1 |
TAAR1 is a trace amine-sensing GPCR enriched in the central nervous system. It regulates dopamine and serotonin monoamine neural circuits, and serves as a therapeutic target for schizophrenia, depression and drug addiction.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1043489-40-2
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분자량 198.17
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화학식 C9H8F2N2O
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SMILES
NC1=N[C@H](CO1)C2=CC=C(C=C2F)F
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Revel FG, et al.. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 2011 May 17;108(20):8485-90. [Content Brief]
[2]. Aleksandrov AA, et al.. The TAAR5 agonist α-NETA causes dyskinesia in mice. Neuroscience letters. 2019 Jun 21;704:208-211. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RO5192022 Related Classifications
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