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Cat. No.: HY-161262

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SB03178

SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research.

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CAS No.: 2952588-12-2
화학식: C₄₄H₅₆F₂N₁₀O₁₀
분자량:922.97

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

SB03178 Chemical Structure

CAS No.: 2952588-12-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research^[1].

Chemical Information

CAS No. 2952588-12-2
분자량 922.97
화학식 C₄₄H₅₆F₂N₁₀O₁₀
SMILES

OC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(N2CCN(CCCOC3=CC4=C(C(NCC(N5[C@H](C#N)CC(F)(F)C5)=O)=O)C=CN=C4C6=C3C=CC=C6)CC2)=O)CC1)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bendre S, et al. Development, preclinical evaluation and preliminary dosimetry profiling of SB03178, a first-of-its-kind benzo[h]quinoline-based fibroblast activation protein-α-targeted radiotheranostic for cancer imaging and therapy. Eur J Med Chem. 2024 Feb 13;268:116238. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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