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SIK-IN-3

SIK-IN-3 (Compound 6B) is an inhibitor for salt-inducible kinase (SIK), which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.3 and 0.8 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC50 of 0.6 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC50 of 3 nM in human macrophages.

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  • CAS No.: 3033845-49-4
  • 화학식: C24H25N5OS
  • 분자량:431.55
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SIK-IN-3 Chemical Structure
    SIK-IN-3 Chemical Structure
CAS No.: 3033845-49-4
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  • SIK-IN-3 Chemical Structure
    SIK-IN-3 Chemical Structure
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  • SIK-IN-3