SMA-12b

SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases.

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  • CAS No.: 1496553-39-9
  • 화학식: C13H22INO2S
  • 분자량:383.29
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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