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Cat. No.: HY-112500

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Spindlactone B

(Synonyms: SPL-B)

Spindlactone B (SPL-B) is a TACC3 inhibitor. Spindlactone B reduces the level of acetylated Microtubules. Spindlactone B can be used in the research of neurological diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1465248-60-5
화학식: C₂₇H₂₂N₂O₅
분자량:454.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Spindlactone B Chemical Structure

CAS No.: 1465248-60-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Spindlactone B (SPL-B) is a TACC3 inhibitor. Spindlactone B reduces the level of acetylated Microtubules. Spindlactone B can be used in the research of neurological diseases^[1].

In Vitro

Spindlactone B (0.25 µg/mL; 48 h) reduces somatic microtubule acetylation, neurite growth, and axon formation in primary mouse cortical neurons, while Cep120 overexpression partially reverses these effects^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1465248-60-5
분자량 454.48
화학식 C₂₇H₂₂N₂O₅
SMILES

O=C1OC2=C(C=CC(O)=C2CN(CC=3C=CN=CC3)CC)C(=C1)C4=CC=5C=CC=CC5OC4=O
Synonyms

SPL-B
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Meka DP, et al. Centrosome-dependent microtubule modifications set the conditions for axon formation. Cell Rep. 2022 Apr 19;39(3):110686. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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