SPR41
SPR41 is a potent SARS-CoV-2 main protease inhibitor with Ki values of 0.184, 0.252, 14.4 µM for SARS-CoV-2 Mpro, hCatL, hCatB, respectively. SPR41 shows antiviral and cytotoxicity.
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- 화학식: C27H37N3O5
- 분자량:483.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Ki: 0.184 µM (SARS-CoV-2 Mpro); 0.252 µM (hCatL); 14.4 µM (hCatB)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
14.5 μM
Compound: SPR41
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Cytotoxicity against human Huh-7 cells overexpressing human ACE2 assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human Huh-7 cells overexpressing human ACE2 assessed as reduction in cell viability incubated for 24 hrs by MTT assay
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[PMID: 36549112] |
Chemical Information
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분자량 483.60
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화학식 C27H37N3O5
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SMILES
O=C(OCC1=CC=CC=C1)N[C@@H](CC2CCCCC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SPR41 Related Classifications
HY-152224 Related Classifications
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