TE-11
Based on 1 Customer Validation
TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.68%
- CAS No.: 160488-11-9
- 화학식: C16H13NO
- 분자량:235.28
-
보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
용액&용해도
- 순도&문서
- References
-
Help & FAQs
Biological Activity
TE-11 (20 µM) inhibits proinflammatory cytokine and RONS production in M1 activated macrophages without a direct antioxidative effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 160488-11-9
-
Appearance Solid
-
분자량 235.28
-
화학식 C16H13NO
-
Color White to light yellow
-
SMILES
O=C1C2=CC=CC=C2CC/C1=C\C3=NC=CC=C3
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (212.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2503 mL | 21.2513 mL | 42.5026 mL | 106.2564 mL |
| 5 mM | 0.8501 mL | 4.2503 mL | 8.5005 mL | 21.2513 mL | |
| 10 mM | 0.4250 mL | 2.1251 mL | 4.2503 mL | 10.6256 mL | |
| 15 mM | 0.2834 mL | 1.4168 mL | 2.8335 mL | 7.0838 mL | |
| 20 mM | 0.2125 mL | 1.0626 mL | 2.1251 mL | 5.3128 mL | |
| 25 mM | 0.1700 mL | 0.8501 mL | 1.7001 mL | 4.2503 mL | |
| 30 mM | 0.1417 mL | 0.7084 mL | 1.4168 mL | 3.5419 mL | |
| 40 mM | 0.1063 mL | 0.5313 mL | 1.0626 mL | 2.6564 mL | |
| 50 mM | 0.0850 mL | 0.4250 mL | 0.8501 mL | 2.1251 mL | |
| 60 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7709 mL | |
| 80 mM | 0.0531 mL | 0.2656 mL | 0.5313 mL | 1.3282 mL | |
| 100 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0626 mL |
TE-11 Related Classifications
HY-173624 Related Classifications
Powered by Bioz