Tilivalline
Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC).
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- CAS No.: 80279-24-9
- 화학식: C20H19N3O2
- 분자량:333.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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CAS No. 80279-24-9
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분자량 333.38
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화학식 C20H19N3O2
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SMILES
O=C1N2CCC[C@]2([C@@H](NC3=C1C=CC=C3O)C4=CNC5=C4C=CC=C5)[H]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Hering NA, et al. Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment. Int J Mol Sci. 2019 Nov 8;20(22):5595. [Content Brief]
[2]. von Tesmar A, et al. Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development. ACS Chem Biol. 2018 Mar 16;13(3):812-819. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)