TTX-P
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C46H35N4O5PS
- 분자량:786.83
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
TTX-P (10 μM) is responsive to alkaline phosphatase (ALP) and correspondingly emits NIR-II fluorescent signals which are suitable for imaging (at 920 nm)[1].
TTX-P (10 μM; HepG2, 4T1, and LO2 cells) can detect and monitor the activity of ALP in cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/C nude mice with 4T1 cells xenografts (female, 4-5 weeks old)[1]
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Dosage:5 mg/kg
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Administration:Intratumoral injection
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Result:Enhanced NIR-II fluorescence signals in a time-dependent manner.
Chemical Information
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분자량 786.83
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화학식 C46H35N4O5PS
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SMILES
CC1=CC=C(C=C1)N(C2=CC=C(C=C2)C3=N/C(S/C3=C\C4=C5OC6=C(C=C5CCC4)C=CC(C7=CC=C(C=C7)OP(O)(O)=O)=C6)=C(C#N)/C#N)C8=CC=C(C=C8)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TTX-P Related Classifications
HY-149835 Related Classifications
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