VHC-7
VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 14750-21-1
- 화학식: C18H15Cl2NO3
- 분자량:364.22
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.1052 μM
Compound: VHC-7
|
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
|
[PMID: 31776060] |
Chemical Information
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CAS No. 14750-21-1
-
분자량 364.22
-
화학식 C18H15Cl2NO3
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SMILES
O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)