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United States

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Cat. No.: HY-W665208

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Zapotin

Zapotin is a member of the polymethoxyflavones, which are natural polyphenols from the group of flavonoid. Zapotin exhibits antidepressant, anticancer, antifungal, and antioxidant activity. Zapotin is a chemopreventive and chemotherapeutic agent. Zapotin can result in a reduction of large aberrant crypt foci in CF-1 mouse model. Zapotin inhibits autophagosome formation. Zapotin has inhibitory activity in mouse mammary organ culture with an IC₅₀ of 50 µg/mL.

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CAS No.: 14813-19-5
화학식: C₁₉H₁₈O₆
분자량:342.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Zapotin Chemical Structure

CAS No.: 14813-19-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	7.6 μM Compound: 1, zapotin	Inhibition of TPA-induced NF-kappaB activity in HepG2 cells Inhibition of TPA-induced NF-kappaB activity in HepG2 cells	[PMID: 17228877]
HL-60	ED₅₀	0.5 μM Compound: 1, zapotin	Induction of differentiation in human HL60 cell line Induction of differentiation in human HL60 cell line	[PMID: 17228877]
T-24	IC₅₀	3.4 μM Compound: 1, zapotin	Inhibition of TPA-induced ODC activity in T24 cells Inhibition of TPA-induced ODC activity in T24 cells	[PMID: 17228877]

Chemical Information

CAS No. 14813-19-5
분자량 342.34
화학식 C₁₉H₁₈O₆
SMILES

COC1=CC=C2OC(C3=C(C=CC=C3OC)OC)=CC(C2=C1OC)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Strawa, J. W., et al., (2021). Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International journal of molecular sciences, 22(24), 13227. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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