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Cat. No.: HY-176419

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KRAS inhibitor-42

KRAS inhibitor-42 (compound 8) is a potent USP7 inhibitor. KRAS inhibitor-42 has high affinity against GDP-bound KRASG12D with a K_i of 2.7 μM.

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Formule: C₃₄H₄₇ClN₈O₄S₂
Masse moléculaire:731.37

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

KRAS inhibitor-42 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

KRAS inhibitor-42 (compound 8) is a potent USP7 inhibitor. KRAS inhibitor-42 has high affinity against GDP-bound KRASG12D with a K_i of 2.7 μM^[1].

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Chemical Information

Masse moléculaire 731.37
Formule C₃₄H₄₇ClN₈O₄S₂
SMILES

OC1=C2C(S/C(N2CCCCCN([C@H]3CC[C@@H](N)CC3)C4=O)=N\S(C5=CN=C(N6CCC(N7CCC(N)CC7)CC6)C4=C5)(=O)=O)=C(Cl)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Waterson AG. Switching It up with New KRAS Inhibitors. J Med Chem. 2025 May 8;68(9):9126-9128. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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KRAS inhibitor-42

Voir tous les produits spécifiques à Isoform Ras

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

KRAS inhibitor-42 Related Classifications

HY-176419 Related Classifications

Bioz

Keywords

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