KRN383 analog
KRN383 analog is an analog of KRN383. KRN383 is an orally active Flt3 inhibitor that inhibits the autophosphorylation of Flt3 bearing internal tandem duplications (ITDs) and the Asp835Tyr (D835Y) point mutation with IC50 values of < or =5.9 and 43 nM, respectively. KRN383 also inhibits the proliferation of the ITD-positive cell lines with IC50 values of < or =2.9 nM. KRN383 can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 919767-02-5
- Formula: C17H17N3O4
- Molecular Weight:327.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 919767-02-5
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Molecular Weight 327.33
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Formula C17H17N3O4
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SMILES
O=C(NC1=CCC(C=C1)OC2=CC=NC3=CC(O)=C(C=C23)OC)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRN383 analog Related Classifications
HY-123201 Related Classifications
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