L-Isoleucine-15N,d10
Based on 1 Customer Validation
L-Isoleucine-15N,d10 is the deuterium and 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C6H3D1015NO2
- Molecular Weight:142.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 73-32-5
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Appearance Solid
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Molecular Weight 142.23
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Formula C6H3D1015NO2
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Color White to off-white
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SMILES
[15NH2][C@]([C@@]([2H])(C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])([2H])C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 25 mg/mL (175.77 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 12.5 mg/mL (87.89 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.0309 mL | 35.1543 mL | 70.3087 mL | 175.7716 mL |
| 5 mM | 1.4062 mL | 7.0309 mL | 14.0617 mL | 35.1543 mL | |
| 10 mM | 0.7031 mL | 3.5154 mL | 7.0309 mL | 17.5772 mL | |
| 15 mM | 0.4687 mL | 2.3436 mL | 4.6872 mL | 11.7181 mL | |
| 20 mM | 0.3515 mL | 1.7577 mL | 3.5154 mL | 8.7886 mL | |
| 25 mM | 0.2812 mL | 1.4062 mL | 2.8123 mL | 7.0309 mL | |
| 30 mM | 0.2344 mL | 1.1718 mL | 2.3436 mL | 5.8591 mL | |
| 40 mM | 0.1758 mL | 0.8789 mL | 1.7577 mL | 4.3943 mL | |
| 50 mM | 0.1406 mL | 0.7031 mL | 1.4062 mL | 3.5154 mL | |
| 60 mM | 0.1172 mL | 0.5859 mL | 1.1718 mL | 2.9295 mL | |
| 80 mM | 0.0879 mL | 0.4394 mL | 0.8789 mL | 2.1971 mL | |
| 100 mM | 0.0703 mL | 0.3515 mL | 0.7031 mL | 1.7577 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.