2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. L742791

L742791 is a β3-AR agonist. L742791 elicits lipolytic response in isolated nonhuman primate adipocytes.

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L742791

L742791 Chemical Structure

CAS No. : 159182-18-0

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L742791 Related Antibodies

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Description

L742791 is a β3-AR agonist. L742791 elicits lipolytic response in isolated nonhuman primate adipocytes[1].

IC50 & Target[1]

Beta-3 adrenergic receptor

 

Cellular Effect
Cell Line Type Value Description References
CHO IC50
120 nM
Compound: 40
Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
[PMID: 9871716]
CHO IC50
170 nM
Compound: 40
Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
[PMID: 9871716]
Molecular Weight

568.42

Formula

C23H25IN2O5S
CAS No.
SMILES

O=S(C1=CC=C(C=C1)I)(NC2=CC=C(C=C2)CCNC[C@@H](COC3=CC=C(C=C3)O)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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L742791 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L742791159182-18-0L 742791L-742791Adrenergic ReceptorBeta ReceptorlipolyticadipocyteInhibitorinhibitorinhibit

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L742791
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HY-117527
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