LAG-3-IN-1
LAG-3-IN-1 (Compound 11) is a LAG-3 inhibitor with a KD of 0.41 μM. LAG-3-IN-1 disrupts the LAG-3/MHCII interaction, enhances IFN-γ secretion and promotes tumor cell killing in cocultures of PBMCs and cancer cells. LAG-3-IN-1 can be used for cancers like ovarian cancer, colon adenocarcinoma and melanoma research.
For research use only. We do not sell to patients.
- Formula: C30H29N3O
- Molecular Weight:447.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 447.57
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Formula C30H29N3O
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SMILES
O=C([C@@H]1[C@H](CN(C1)CC2=NC=CC=C2)C3=CC=CC=C3)NCC4=CC=C(C=C4)C5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topics Organoid Co-culture Models in Tumor Immunology
Organoid co-culture models in tumor immunology are three-dimensional experimental systems that combine patient-derived or stem cell-derived tumor organoids with immune cells and other components of the tumor microenvironment to recapitulate tumor-immune interactions in vitro.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)