country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-W030978

Copy Link Print Information

Lamivudine impurity 5

Lamivudine impurity 5 is an impurity of Lamivudine.

For research use only. We do not sell to patients.

CAS No.: 134680-32-3
Formula: C₈H₁₁N₃O₃S
Molecular Weight:229.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (239 KB)

Lamivudine impurity 5 Chemical Structure

CAS No.: 134680-32-3

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Lamivudine impurity 5 is an impurity of Lamivudine.

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	CC₅₀	2.7 μM Compound: (+)-BCH-189	Cytotoxicity against human CEM cells Cytotoxicity against human CEM cells	[PMID: 37393791]
HepG2 2.2.15	CC₅₀	>100 μM Compound: LAM	Cytotoxicity against human HepG2.2.15 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2.2.15 cells after 72 hrs by MTT assay	[PMID: 29459146]
HepG2 2.2.15	CC₅₀	876.2 μM Compound: 3TC	Cytotoxicity against human HepG2.215 cells assessed as reduction in cell viability after 3 days by MTT assay Cytotoxicity against human HepG2.215 cells assessed as reduction in cell viability after 3 days by MTT assay	[PMID: 29627260]
HepG2 2.2.15	IC₅₀	2.09 μM Compound: 3TC	Antiviral activity against HBV infected in human HepG2(2.2.15) cells assessed as inhibition of viral DNA replication after 48 hrs by SYBR Green based RT-PCR method Antiviral activity against HBV infected in human HepG2(2.2.15) cells assessed as inhibition of viral DNA replication after 48 hrs by SYBR Green based RT-PCR method	10.1039/C6MD00008H
MT4	CC₅₀	>87 μM Compound: Lamivudine	Cytotoxicity against human MT4 cells after 5 days MTT assay Cytotoxicity against human MT4 cells after 5 days MTT assay	[PMID: 27112451]
MT4	CC₅₀	>87.24 μM Compound: 3TC	Cytotoxicity against mock infected human MT4 cells after 4 days by MTT assay Cytotoxicity against mock infected human MT4 cells after 4 days by MTT assay	[PMID: 26994843]
MT4	CC₅₀	>87.24 μM Compound: 3TC	Cytotoxicity against mock-infected human MT4 cells incubated for 5 days by MTT assay Cytotoxicity against mock-infected human MT4 cells incubated for 5 days by MTT assay	[PMID: 34090079]
MT4	EC₅₀	2.2 μM Compound: Lamivudine	Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 5 days by MTT assay Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 5 days by MTT assay	[PMID: 27112451]
MT4	EC₅₀	2.53 μM Compound: 3TC	Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as cell viability after 4 days by MTT assay Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as cell viability after 4 days by MTT assay	[PMID: 26994843]
MT4	EC₅₀	9.9 μM Compound: 3TC	Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as cell viability after 4 days by MTT assay Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as cell viability after 4 days by MTT assay	[PMID: 26994843]

Chemical Information

CAS No. 134680-32-3
Molecular Weight 229.25
Formula C₈H₁₁N₃O₃S
SMILES

O=C1N([C@@H]2O[C@H](CO)SC2)C=CC(N)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.