LH10
LH10 is a fexaramine-based agonist for FXR with an EC50 of 0.14 μM. LH10 exhibits liver protection efficacy, ameliorates the alpha naphthylisothiocyanate (ANIT)-induced cholestasis, APAP (HY-66005)-induced acute liver injury and non-alcoholic steatohepatitis (NASH) in mouse models.
For research use only. We do not sell to patients.
- Formula: C34H33N3O2
- Molecular Weight:515.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: FXR (0.14 μM)
Chemical Information
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Molecular Weight 515.64
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Formula C34H33N3O2
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SMILES
O=C(C1CCCCC1)N(CC2=CC=C(C3=CC=C4C=COC4=C3)C=C2)C5=CC=CC(C6=CN(C7CC7)N=C6)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LH10 Related Classifications
HY-168327 Related Classifications
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