Lifibrol
Lifibrol is a potent and oral activity hypolipidemic agent. Lifibrol decreases the plasma total cholesterol. Lifibrol has the potential for the research of hypercholesterolemia.
For research use only. We do not sell to patients.
- CAS No.: 96609-16-4
- Formula: C21H26O4
- Molecular Weight:342.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male TUC-Sprague-Dawley rats[2]
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Dosage:15, 50 mg/kg
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Administration:P.o; daily for 6 days
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Result:Decreased the plasma total cholesterol.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 96609-16-4
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Molecular Weight 342.43
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Formula C21H26O4
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SMILES
O=C(C1=CC=C(C=C1)OCC(CCC2=CC=C(C=C2)C(C)(C)C)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Locker PK, et al. Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group. Clin Pharmacol Ther. 1995 Jan;57(1):73-88. [Content Brief]
[2]. Bell FP, et al. Action of the new hypolipidemic agent lifibrol (K12.148) on lipid homeostasis in normal rats: plasma lipids, hepatic sterologenesis, and the fate of injected [14C]acetate. Lipids. 1993 Dec;28(12):1079-85. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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