Hydroxy Fatty Acids

15-Hydroxystearic acid is a hydroxylated long-chain fatty acid with high binding affinity to SlSCPx-2.

17-Hydroxystearic acid isolable from Torulopsis magnoliae fermentation oil. 17-Hydroxystearic acid is a saturated C₁₈ ω2-hydroxy fatty acid existing in D- and L-enantiomeric forms.

8(R)-Hydroxylinoleic acid (8-HPODE; PsiBα) is an oxygenated unsaturated C₁₈ fatty acid that regulates fungal sporulation. 8(R)-Hydroxylinoleic acid increases the level of ascospores and decreases the level of conidia in fungi. 8(R)-Hydroxylinoleic acid can be used in studies related to fungi.

5-Hydroxyhexanoic acid is a normal monohydroxy carboxylic acid degradation product of
fatty acids with medium chain lengths (particularly hexanoic acid). 5-Hydroxyhexanoic acid functions as a predictor of early renal functional decline in type 2 diabetes with microalbuminuria.

(R)-3-Hydroxydecanoic acid is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

(2S)-2-Hydroxy-2-isopropylsuccinic acid (Ds-α-isopropylmalate) is an intermediate in the biosynthesis of Leucine.

11-Hydroxyundecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

13-Hydroxytridecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

Feruloyl-CoA (Feruloyl-coenzyme A) is a cinnamoyl-CoA ester substrate involved in the biosynthesis of lignin and coumarin in plants. Feruloyl-CoA acts as a substrate for cinnamoyl-CoA reductase 1-dependent reduction reaction with NADPH to produce cinnamaldehyde. Feruloyl-CoA is a precursor that generates Scopoletin (HY-N0342) via spontaneous trans/cis isomerization and lactonization of its side chain.

10(R)-Hydroxystearic acid is a derivative of Oleic acid (HY-N1446). 10(R)-Hydroxystearic acid can be biocatalytically produced by Lactobacillus rhamnosus ATCC 53103.

10(S)-Hydroxystearic acid ((S)-10-Hydroxyoctadecanoic acid; (S)-10-HSA) is a hydroxy fatty acid and a derivative of Oleic acid (HY-N1446). 10(S)-Hydroxystearic acid can be used for the research of infection.

3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism.

3-Hydroxyadipyl-CoA (3-Hydroxyadipoyl-coenzyme A) is a coenzyme A derivative.

Nemotinic acid has the activity against Gram-positive bacteria, mycobacterium and fungus, and also against Gram-negative bacteria, but the activity is weak.

Agrocybin is an antifungal peptide that exerts antifungal activity against several fungal species but lacks inhibitory activity against bacteria. Agrocybin attenuates the activity of HIV-1 reverse transcriptase.

2,3-Dihydroxybutanoic acid is an anticancer agent that can be extracted from the leaves of Corydalis. 2,3-Dihydroxybutanoic acid has anticancer activity both in vitro and in vivo and is lethal to Ehrlich ascites tumor cells.

10(S)-HOME is an oxylipin.

15,16-Dihydroxy-9Z,12Z-octadecadienoic acid is a natural product.

9,12,13-Trihydroxy-10-octadecenoic acid is an antimicrobial agent.

Ricinelaidic acid, a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the K_i of 2 μM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC₅₀=10 and 7 μM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats.