Sphingolipids

1-Deoxysphingosine is elevated in lymphoblasts of individuals with hereditary sensory neuropathy type 1 (HSAN1) disorder; it features a (4E) double bond in its structure and is produced through the catabolism of 1-deoxyceramide catalyzed by the ceramidase enzyme, classifying it as an unsaturated deoxy-sphingoid base.

Sphingosyl PE (d18:1) is a kind of biochemical reagent.

N-12:0-1-Deoxysphinganine is a kind of biochemical reagent.

C4 Dihydroceramide is a biochemical assay reagent.

C6 Biotin glucosylceramide (d18:1/6:0) (C6 Glucosylceramide-biotin; N-Hexanoyl-biotin-glucosylceramide) is an ester product.

C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.

(±)-2'-hydroxy Ceramide (d18:0/18:0) is a sphingomyelin that can be isolated from mammalian platelets stimulation by ADP.

Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity.

Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca²⁺.

Soyacerebroside II is a calcium ionophoretic sphingoglycolipid that can be isolated from Soybean.

Momor-cerebroside I is a cerebroside compound isolated from Momordica charantia.

W140 (TFA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Tetracosanoyl-sulfatide is an endogenous metabolite present in Urine that can be used for the research of Mild Metachromatic Leukodystrophy.

Safingol is a lyso-sphingolipid PKC (protein kinase C ) inhibitor.

D-threo-PPMP is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP can block karyokinesis and reduce cyst production.

C8 Dihydroceramide is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro.

C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) is a ganglioside.

C24:1 GM3 Ceramide (d18:1/24:1) is a globoside that can be used to prepare lipid nanoparticles for drug delivery.

14:0 Dihydro SM (d18:0/14:0) is a sphingomyelin.