Lofendazam
Lofendazam is a major metabolite of Arfendazam. Lofendazam acts as a positive allosteric modulator/partial agonist of GABAa receptor, with IC50 values of 10.1 nM and 9.1 nM in bovine cerebral cortex and bovine cerebellum, respectively; its in vivo ED50 via oral administration is 233 µmol/kg.
For research use only. We do not sell to patients.
- CAS No.: 29176-29-2
- Formula: C15H13ClN2O
- Molecular Weight:272.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 29176-29-2
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Molecular Weight 272.73
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Formula C15H13ClN2O
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SMILES
O=C1N(C=2C=CC=CC2)C3=CC(Cl)=CC=C3NCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)