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  4. lucPpy-IN-1

lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 μM. lucPpy-IN-1 can be used for the research of target’s agentgability.

For research use only. We do not sell to patients.

lucPpy-IN-1 Chemical Structure

lucPpy-IN-1 Chemical Structure

CAS No. : 546100-66-7

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5 mg USD 58 In-stock
10 mg USD 105 In-stock
25 mg USD 225 In-stock
50 mg USD 360 In-stock
100 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

lucPpy-IN-1 Related Antibodies

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Description

lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 μM. lucPpy-IN-1 can be used for the research of target’s agentgability[1].

IC50 & Target

IC50: 4.0 µM (lucPpy)[1]
In Vitro

lucPpy-IN-1 (0.1 nM-100 µM) inhibits activity of lucPpy with an IC50 value of 4.0 µM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

lucPpy-IN-1 Related Antibodies
Molecular Weight

409.48

Formula

C25H23N5O
CAS No.
Appearance

Solid

Color

Pink to orange

SMILES

O=C(C1=CC(C2=CC=C(C)C=C2)=NC3=CC=CC=C13)N4CCN(C5=NC=CC=N5)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (305.27 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4421 mL 12.2106 mL 24.4212 mL
5 mM 0.4884 mL 2.4421 mL 4.8842 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4421 mL 12.2106 mL 24.4212 mL 61.0530 mL
5 mM 0.4884 mL 2.4421 mL 4.8842 mL 12.2106 mL
10 mM 0.2442 mL 1.2211 mL 2.4421 mL 6.1053 mL
15 mM 0.1628 mL 0.8140 mL 1.6281 mL 4.0702 mL
20 mM 0.1221 mL 0.6105 mL 1.2211 mL 3.0527 mL
25 mM 0.0977 mL 0.4884 mL 0.9768 mL 2.4421 mL
30 mM 0.0814 mL 0.4070 mL 0.8140 mL 2.0351 mL
40 mM 0.0611 mL 0.3053 mL 0.6105 mL 1.5263 mL
50 mM 0.0488 mL 0.2442 mL 0.4884 mL 1.2211 mL
60 mM 0.0407 mL 0.2035 mL 0.4070 mL 1.0176 mL
80 mM 0.0305 mL 0.1526 mL 0.3053 mL 0.7632 mL
100 mM 0.0244 mL 0.1221 mL 0.2442 mL 0.6105 mL
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lucPpy-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

lucPpy-IN-1546100-66-7Fluorescent DyedruggabilityPhotinus pyralisATP-dependentInhibitorinhibitorinhibit

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