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Cat. No.: HY-D2321

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Lyso Flipper-TR 29

Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form.

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CAS No.: 2324152-35-2
Formule: C₃₅H₃₇N₅O₄S₆
Masse moléculaire:784.09

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Lyso Flipper-TR 29 Chemical Structure

CAS No.: 2324152-35-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form^[1].

In Vitro

Lyso Flipper-TR 29 enters lysosomes by transient deprotonation to diffuse in neutral form across the hydrophobic membrane, while its return to the cytosol is not possible because low pH≈5 within lysosomes prevents transient deprotonation. Lyso Flipper-TR 29 tracks also late endosomes, but fails to label early endosomes (EE) because their internal pH >6 is too high to prevent transient deprotonation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2324152-35-2
Masse moléculaire 784.09
Formule C₃₅H₃₇N₅O₄S₆
SMILES

CC1=C(C#N)SC(C2=C3C(C)=C(C4=C(C)C(SC5=C6SC(COCC7=CN(CCCCCCN8CCOCC8)N=N7)=C5C)=C6S4)S2)=C1S3(=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xiao-Xiao Chen, et al. Fluorescent Flippers: Small-Molecule Probes to Image Membrane Tension in Living Systems. Angew Chem Int Ed Engl. 2023 May 8;62(20):e202217868. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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