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Cat. No.: HY-187233

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MAC-0040599

MAC-0040599 is a synthetic antibacterial compound that exhibits inhibitory effects against various strains including Burkholderia cenocepacia K56-2 and Pseudomonas aeruginosa. MAC-0040599 can be used in studies related to bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 28783-31-5
Formula: C₆H₅NO₂S
Molecular Weight:155.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MAC-0040599 Chemical Structure

CAS No.: 28783-31-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

MAC-0040599 (up to 64 μg/mL; 22 h) inhibits the growth of Burkholderia cenocepacia K56-2 with an MIC of 32 μg/mL, 4 other Bcc strains with MICs ≤32 μg/mL, and Pseudomonas aeruginosa PAO1 with an MIC of 64 μg/mL^[1].
MAC-0040599 (48 h) exerts bactericidal activity against 5 of 10 tested Bcc strains at concentrations ≤64 μg/mL^[1].
MAC-0040599 (20 h treatment, 1 h Resazurin (HY-118540) incubation) inhibits pre-formed biofilms of Burkholderia cenocepacia K56-2 and 4 other Bcc strains at concentrations ≤64 μg/mL^[1].
MAC-0040599 (25-250 μg/mL; 1 h) shows minimal hemolytic activity against sheep red blood cells at concentrations up to 250 μg/mL, with all values below the 5-10% moderate hemolysis threshold^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 28783-31-5
Molecular Weight 155.17
Formula C₆H₅NO₂S
SMILES

O=[N+](/C=C/C1=CSC=C1)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Selin C, et al. A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia. PloS one. 2015;10(6):e0128587.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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