Magmas-IN-1
Magmas-IN-1 (compound 9) is a small molecule Magmas inhibitor (SMMI). Magmas is mitochondria associated,granulocyte-macrophage colony stimulating factor signaling molecule,as well as a GM-CSF inducible gene in myeloid cells. Magmas-IN-1 inhibits Magmas and modulates mitochondrial function. Magmas-IN-1 also inhibits proliferation in yeast at 4 μM.
For research use only. We do not sell to patients.
- CAS No.: 1251957-89-7
- Formula: C20H27N3O
- Molecular Weight:325.45
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Magmas[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LN-229 | IC50 |
6.54 μM
Compound: BT-9
|
Anticancer activity against human LN-229 cells assessed as cell growth inhibition inhibition incubated for 3 days
Anticancer activity against human LN-229 cells assessed as cell growth inhibition inhibition incubated for 3 days
|
[PMID: 37201660] |
| U-251 | IC50 |
5.06 μM
Compound: BT-9
|
Anticancer activity against human U-251 cells assessed as cell growth inhibition inhibition incubated for 3 days
Anticancer activity against human U-251 cells assessed as cell growth inhibition inhibition incubated for 3 days
|
[PMID: 37201660] |
Chemical Information
-
CAS No. 1251957-89-7
-
Molecular Weight 325.45
-
Formula C20H27N3O
-
SMILES
CCC1=C(/C(CCC1(C)C)=C/C2=CC=C(C=C2)C(NC(N)=N)=O)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)