MALT1-IN-9
MALT1-IN-9 is a potent MALT1 protease inhibitor with a IC50 of <500 nM in Raji MALT1-GloSensor cells. MALT1-IN-9 has anticancer effects (WO2021000855A1; Compound 5).
For research use only. We do not sell to patients.
- CAS No.: 2577170-77-3
- Formula: C16H12ClF3N6O
- Molecular Weight:396.75
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: <500 nM (MALT1 protease in Raji MALT1-GloSensor cells)[1]
Chemical Information
-
CAS No. 2577170-77-3
-
Molecular Weight 396.75
-
Formula C16H12ClF3N6O
-
SMILES
O=C(NC1=CC(C(F)(F)F)=NC=C1)NC2=C(C3CC3)C4=NC(Cl)=CN4N=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)