Malvidin chloride
Based on 1 Customer Validation
Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 97.05%
- CAS No.: 643-84-5
- Formula: C17H15ClO7
- Molecular Weight:366.75
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
9 μM
Compound: Malvidin
|
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
|
[PMID: 28159411] |
| RAW264.7 | IC50 |
9 μM
Compound: Malvidin
|
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
|
[PMID: 28384544] |
| RAW264.7 | IC50 |
9 μM
Compound: Malvidin
|
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
|
[PMID: 35932905] |
Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1].
The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:U937 cells
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Concentration:0~80 μg/mL
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Incubation Time:96 hours
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Result:Showed cytotoxic activity in a dose-dependent pattern.
Chemical Information
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CAS No. 643-84-5
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Appearance Solid
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Molecular Weight 366.75
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Formula C17H15ClO7
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Color Brown to dark brown
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SMILES
OC1=CC(O)=C2C=C(C(C3=CC(OC)=C(C(OC)=C3)O)=[O+]C2=C1)O.[Cl-]
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Synonyms
Syringidin
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)