1. Neuronal Signaling
  2. Monoamine Oxidase
  3. MAO-B-IN-15

MAO-B-IN-15 

Cat. No.: HY-151209
Handling Instructions

MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease.

For research use only. We do not sell to patients.

MAO-B-IN-15 Chemical Structure

MAO-B-IN-15 Chemical Structure

CAS No. : 2032436-79-4

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Description

MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1].

IC50 & Target[1]

hMAO-B

13.5 μM (IC50)

hMAO-A

>100 μM (IC50)

In Vitro

MAO-B-IN-15 (Compound 4i, 0.01-1000 μM, 1 h) dose-dependently inhibits MAO-B activity[1].
MAO-B-IN-15 (10 μM, 24 h) has no effect on cell viability of SH-SY5Y cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

287.33

Formula

C17H18FNO2

CAS No.
SMILES

COC1=CC2=C(C=C1OC)CCN(C3=CC=C(F)C=C3)C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MAO-B-IN-15
Cat. No.:
HY-151209
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