MAO-B-IN-32
MAO-B-IN-32 is an inhibitor of MAO-B (IC50 = 16 nM).MAO-B-IN-32 increases dopamine concentration in the brain by inhibiting MAO-B activity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C20H19FO4
- Masse moléculaire:342.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
|
MAO-B 16 nM (IC50) |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | GI50 |
10.2 μM
Compound: 9f
|
Growth inhibition of HEK293 cells incubated for 72 hrs by MTT assay
Growth inhibition of HEK293 cells incubated for 72 hrs by MTT assay
|
[PMID: 38746894] |
| MDA-MB-231 | GI50 |
>20 μM
Compound: 9f
|
Growth inhibition of human MDA-MB-231 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells incubated for 72 hrs by MTT assay
|
[PMID: 38746894] |
| SH-SY5Y | GI50 |
>20 μM
Compound: 9f
|
Growth inhibition of human SH-SY5Y cells incubated for 72 hrs by MTT assay
Growth inhibition of human SH-SY5Y cells incubated for 72 hrs by MTT assay
|
[PMID: 38746894] |
Chemical Information
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Masse moléculaire 342.36
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Formule C20H19FO4
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SMILES
O=C1C=C(C2=CC=C(OCC(C)C)C=C2)OC3=C1C(F)=CC(OC)=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)