1. Membrane Transporter/Ion Channel
  2. Na+/K+ ATPase
  3. Marinobufogenin

Marinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma.

For research use only. We do not sell to patients.

Marinobufogenin Chemical Structure

Marinobufogenin Chemical Structure

CAS No. : 470-42-8

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5 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Marinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma[1].

IC50 & Target

IC50: Na+/K+ ATPase[1]

Molecular Weight

400.51

Formula

C24H32O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([C@H](O3)C[C@@H]2C(C=C4)=COC4=O)[C@]5([C@]([H])(CC1)[C@]6(C)[C@@](C[C@H](CC6)O)(CC5)O)[H]

Structure Classification
Initial Source

toad

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (249.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4968 mL 12.4841 mL 24.9682 mL
5 mM 0.4994 mL 2.4968 mL 4.9936 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4968 mL 12.4841 mL 24.9682 mL 62.4204 mL
5 mM 0.4994 mL 2.4968 mL 4.9936 mL 12.4841 mL
10 mM 0.2497 mL 1.2484 mL 2.4968 mL 6.2420 mL
15 mM 0.1665 mL 0.8323 mL 1.6645 mL 4.1614 mL
20 mM 0.1248 mL 0.6242 mL 1.2484 mL 3.1210 mL
25 mM 0.0999 mL 0.4994 mL 0.9987 mL 2.4968 mL
30 mM 0.0832 mL 0.4161 mL 0.8323 mL 2.0807 mL
40 mM 0.0624 mL 0.3121 mL 0.6242 mL 1.5605 mL
50 mM 0.0499 mL 0.2497 mL 0.4994 mL 1.2484 mL
60 mM 0.0416 mL 0.2081 mL 0.4161 mL 1.0403 mL
80 mM 0.0312 mL 0.1561 mL 0.3121 mL 0.7803 mL
100 mM 0.0250 mL 0.1248 mL 0.2497 mL 0.6242 mL
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Marinobufogenin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Marinobufogenin
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HY-N6574
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