1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MC-GGFG-DX8951

MC-GGFG-DX8951 

Cat. No.: HY-114233
Handling Instructions

MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.

For research use only. We do not sell to patients.

MC-GGFG-DX8951 Chemical Structure

MC-GGFG-DX8951 Chemical Structure

CAS No. : 1600418-29-8

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker[1].

IC50 & Target

Camptothecins

 

Molecular Weight

946.97

Formula

C₄₉H₅₁FN₈O₁₁

CAS No.

1600418-29-8

SMILES

O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[[email protected]@H]5NC(CNC([[email protected]@H](NC(CNC(CNC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=C4C5=C3C8)N8C2=O)[[email protected]@]1(O)CC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
MC-GGFG-DX8951
Cat. No.:
HY-114233
Quantity: