1. Apoptosis
  2. MDM-2/p53
  3. MDM2-IN-21

MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer.

For research use only. We do not sell to patients.

MDM2-IN-21 Chemical Structure

MDM2-IN-21 Chemical Structure

CAS No. : 939981-88-1

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Description

MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].

IC50 & Target

MDM2[1]

In Vitro

The IC50 values of MDM2-IN-21 are 0.03 μM and 0.8 μM in homogeneous time resolved fluorescence (HTRF) assay and the wild-type p53 cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

607.61

Formula

C34H40Cl2N4O2

CAS No.
SMILES

C[C@]1(C2=CC=C(C=C2)Cl)N(C(C3=C(C=C(C=C3)C(C)(C)C)OCC)=N[C@]1(C4=CC=C(C=C4)Cl)C)C(N5CCNCC5)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MDM2-IN-21 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MDM2-IN-21
Cat. No.:
HY-139458
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