MDM2-IN-26
MDM2-IN-26 (compound A3) is an MDM2 inhibitor that can activate the tumor suppressor function of p53 by blocking the interaction between MDM2 and p53 (MDM2 is the main negative regulator of p53). MDM2-IN-26 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1818393-11-1
- Formula: C32H32Cl2F3N3O4
- Molecular Weight:650.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MDM2[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SJSA-1 | IC50 |
0.17 μM
Compound: 57
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Cytotoxicity against p53 expressing human SJSA1 cells assessed as cell growth inhibition by WST8 assay
Cytotoxicity against p53 expressing human SJSA1 cells assessed as cell growth inhibition by WST8 assay
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[PMID: 28339198] |
Chemical Information
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CAS No. 1818393-11-1
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Molecular Weight 650.52
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Formula C32H32Cl2F3N3O4
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SMILES
OC(C12CCC(CC2)(NC([C@H]3[C@H](C4=CC=CC(Cl)=C4F)[C@@]5(C(C=CC(Cl)=C6)=C6NC5=O)C7(CCC(F)(F)CC7)N3)=O)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MDM2-IN-26 Related Classifications
HY-162247 Related Classifications
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