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Cat. No.: HY-105636

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Metallibure

(Synonyms: ICI 33828; Methallibure)

Methallibure (ICI 33828) is a dithiocarbamoylhydrazine derivative and gonadotropic function blocker. Methallibure can block the action of pituitary gonadotropins in teleost fishes and inhibit germ cell maturation. Methallibure does not affect the histological structure of the thyroid gland but reduces the nuclear volume of thyroid epithelial cells. Methallibure can be used in the research of endocrine diseases.

For research use only. We do not sell to patients.

CAS No.: 926-93-2
Formula: C₇H₁₄N₄S₂
Molecular Weight:218.34

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (265 KB)

Metallibure Chemical Structure

CAS No.: 926-93-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 926-93-2
Appearance Solid
Molecular Weight 218.34
Formula C₇H₁₄N₄S₂
Color White to off-white
SMILES

CNC(NNC(NC(C=C)C)=S)=S
Synonyms

ICI 33828; Methallibure
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hoar W S, et al. Inhibition of the pituitary gonadotropic activity of fishes by a dithiocarbamoylhydrazine derivative (ICI 33,828). General and Comparative Endocrinology, 1967, 8(1): 101-109.

[2]. Löw O, et al. Morphometrie an indokrinen Organen. II. Karyometrie an Schilddrüsen von Hunden und Schweinen nach Applikation von TURISYNCHRON und SUISYNCHRON [Morphometry of endocrine organs. 2. Karyometry of dog and swine thyroid glands following administration of TURISYNCHRON and SUISYNCHRON]. Arch Exp Veterinarmed. 1974;28(5):725-30. German. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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