2. Others GPCR/G Protein
  3. Drug Derivative GnRH Receptor
  4. Metallibure

Methallibure (ICI 33828) is a dithiocarbamoylhydrazine derivative and gonadotropic function blocker. Methallibure can block the action of pituitary gonadotropins in teleost fishes and inhibit germ cell maturation. Methallibure does not affect the histological structure of the thyroid gland but reduces the nuclear volume of thyroid epithelial cells. Methallibure can be used in the research of endocrine diseases.

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Metallibure

Metallibure Chemical Structure

CAS No. : 926-93-2

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Metallibure Related Antibodies

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Description

Methallibure (ICI 33828) is a dithiocarbamoylhydrazine derivative and gonadotropic function blocker. Methallibure can block the action of pituitary gonadotropins in teleost fishes and inhibit germ cell maturation. Methallibure does not affect the histological structure of the thyroid gland but reduces the nuclear volume of thyroid epithelial cells. Methallibure can be used in the research of endocrine diseases[1][2].

Molecular Weight

218.34

Formula

C7H14N4S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CNC(NNC(NC(C=C)C)=S)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Metallibure Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metallibure926-93-2ICI 33828 MethallibureICI33828ICI-33828Drug DerivativeGnRH ReceptorDrug derivativeGonadotropin releasing hormone receptorGNRHRdithiocarbamoylhydrazine derivativeteleost fishesgerm cellthyroid epithelial cellsInhibitorinhibitorinhibit

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