Methionol
Based on 1 Customer Validation
Methionol is a sulfur-containing flavor compound and also a component of aggregation pheromones produced by males. Methionol exists in fermented coconut milk and wine. Methionol has an odor similar to boiled cabbage, and imparts cauliflower-like off-flavors to wine when its content exceeds the perception threshold. Methionol attracts both male and female adults of Knulliana cincta cincta, and mainly attracts female adults of Elaphidion mucronatum.
For research use only. We do not sell to patients.
- CAS No.: 505-10-2
- Formula: C4H10OS
- Molecular Weight:106.19
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Methionol is a highly potent aroma-active compound with a boiled cabbage odour in both aerated and non-aerated coconut cream fermented by Kluyveromyces lactis KL71, exhibiting high Charm values, OSVs, and FDVs consistent with strong odour activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:both sexes[2]
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Dosage:25 mg
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Administration:dispensed from polyethylene sachets
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Result:Captured 15 Knulliana cincta cincta adults in Illinois, with a mean of 1.4 beetles per replicate, significantly higher than captures in traps baited with sulfoxide, methionol + sulfoxide, or solvent control (F3,34=22.3, P<0.0001, Tukey test, P<0.05).
Captured 9 Elaphidion mucronatum adults in Illinois, with 78% in methionol-baited traps, resulting in a mean of 1.8 beetles per replicate, significantly higher than other treatments (F3,15=11.7, P=0.0013).
Captured 123 Knulliana cincta cincta adults in Iowa, with a mean of 14.2 beetles per replicate, significantly higher than captures in traps baited with sulfoxide or solvent control (F3,23=16.6, P=0.0009, Tukey test, P<0.05), while captures in methionol + sulfoxide-baited traps were intermediate.
Chemical Information
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CAS No. 505-10-2
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Appearance Liquid (Density: 1.03 g/cm3)
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Molecular Weight 106.19
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Formula C4H10OS
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SMILES
OCCCSC
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Synonyms
3-Hydroxypropyl methyl sulfide; 3-Methylmercapto-1-propanol; 4-Thiapentan-1-ol; gamma-Hydroxypropyl methyl sulfide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (1883.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Seow YX, et al. Production of flavour-active methionol from methionine metabolism by yeasts in coconut cream. International journal of food microbiology. 2010 Oct 15;143(3):235-40. [Content Brief]
[2]. Rice ME, et al. Methionol, a Sulfur-Containing Pheromone Component from the North American Cerambycid Beetle Knulliana cincta cincta. Journal of chemical ecology. 2022 Apr;48(4):347-358. [Content Brief]
[3]. Silva Ferreira AC, et al. Influence of some technological parameters on the formation of dimethyl sulfide, 2-mercaptoethanol, methionol, and dimethyl sulfone in port wines. Journal of agricultural and food chemistry. 2003 Jan 29;51(3):727-32. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.4171 mL | 47.0854 mL | 94.1708 mL | 235.4271 mL |
| 5 mM | 1.8834 mL | 9.4171 mL | 18.8342 mL | 47.0854 mL | |
| 10 mM | 0.9417 mL | 4.7085 mL | 9.4171 mL | 23.5427 mL | |
| 15 mM | 0.6278 mL | 3.1390 mL | 6.2781 mL | 15.6951 mL | |
| 20 mM | 0.4709 mL | 2.3543 mL | 4.7085 mL | 11.7714 mL | |
| 25 mM | 0.3767 mL | 1.8834 mL | 3.7668 mL | 9.4171 mL | |
| 30 mM | 0.3139 mL | 1.5695 mL | 3.1390 mL | 7.8476 mL | |
| 40 mM | 0.2354 mL | 1.1771 mL | 2.3543 mL | 5.8857 mL | |
| 50 mM | 0.1883 mL | 0.9417 mL | 1.8834 mL | 4.7085 mL | |
| 60 mM | 0.1570 mL | 0.7848 mL | 1.5695 mL | 3.9238 mL | |
| 80 mM | 0.1177 mL | 0.5886 mL | 1.1771 mL | 2.9428 mL | |
| 100 mM | 0.0942 mL | 0.4709 mL | 0.9417 mL | 2.3543 mL |
Methionol Related Classifications
HY-Y1002 Related Classifications
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- Methionol
- 505-10-2
- 3-Hydroxypropyl methyl sulfide
- 3-Methylmercapto-1-propanol
- 4-Thiapentan-1-ol
- gamma-Hydroxypropyl methyl sulfide
- Biochemical Assay Reagents
- Sex Pheromone
- L-methionine
- Elaphidion mucronatum
- Saccharomyces cerevisiae EC1118
- Kluyveromyces lactis KL71
- Ehrlich pathway
- wines
- fermented coconut cream
- yeast
- Knulliana cincta cincta
- Port wines
- Inhibitor
- inhibitor
- inhibit