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Cat. No.: HY-N0950

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(-)-Conocarpan

(-)-Conocarpan is a natural compound that can be isolated from various species of Krarneria.

For research use only. We do not sell to patients.

CAS No.: 56319-02-9
Formula: C₁₈H₁₈O₂
Molecular Weight:266.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

(-)-Conocarpan Chemical Structure

CAS No.: 56319-02-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

(-)-Conocarpan is a natural compound that can be isolated from various species of Krarneria^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	19.5 μM Compound: 7	Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method	[PMID: 21800856]
HEK293	IC₅₀	>20 μM Compound: 7	Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay	[PMID: 21800856]

Chemical Information

CAS No. 56319-02-9
Molecular Weight 266.33
Formula C₁₈H₁₈O₂
SMILES

OC1=CC=C([C@@H]2OC3=CC=C(/C=C/C)C=C3[C@H]2C)C=C1
Structure Classification
- Phenylpropanoids
- Lignans
- Phenols
- Monophenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S A Silva, et al. Krametosan, a new trinorlignan from the roots of Krameria tomentosa. Nat Prod Lett. 2001;15(5):323-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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