1. Metabolic Enzyme/Protease
  2. Aldose Reductase
  3. MK204

MK204 is an aldose reductase (AR) inhibitor that can be used in diabetes research.

For research use only. We do not sell to patients.

MK204

MK204 Chemical Structure

CAS No. : 1959605-73-2

Size Price Stock Quantity
5 mg Get quote 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
10 mg Get quote 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
25 mg Get quote 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
50 mg Get quote 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
100 mg Get quote 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks
200 mg   Get quote  
500 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MK204 is an aldose reductase (AR) inhibitor that can be used in diabetes research[1].

Molecular Weight

714.22

Formula

C16H9Br5ClNO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)COC1=CC(Cl)=CC=C1C(NCC2=C(Br)C(Br)=C(Br)C(Br)=C2Br)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (140.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4001 mL 7.0006 mL 14.0013 mL
5 mM 0.2800 mL 1.4001 mL 2.8003 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.7%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4001 mL 7.0006 mL 14.0013 mL 35.0032 mL
5 mM 0.2800 mL 1.4001 mL 2.8003 mL 7.0006 mL
10 mM 0.1400 mL 0.7001 mL 1.4001 mL 3.5003 mL
15 mM 0.0933 mL 0.4667 mL 0.9334 mL 2.3335 mL
20 mM 0.0700 mL 0.3500 mL 0.7001 mL 1.7502 mL
25 mM 0.0560 mL 0.2800 mL 0.5601 mL 1.4001 mL
30 mM 0.0467 mL 0.2334 mL 0.4667 mL 1.1668 mL
40 mM 0.0350 mL 0.1750 mL 0.3500 mL 0.8751 mL
50 mM 0.0280 mL 0.1400 mL 0.2800 mL 0.7001 mL
60 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5834 mL
80 mM 0.0175 mL 0.0875 mL 0.1750 mL 0.4375 mL
100 mM 0.0140 mL 0.0700 mL 0.1400 mL 0.3500 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
MK204
Cat. No.:
HY-120208
Quantity:
MCE Japan Authorized Agent: