ML-SI3 (Standard)

(Synonyms: ML-SI3 (cis/trans mix) (Standard))

ML-SI3 (Standard) is the analytical standard of ML-SI3 (HY-139426). This product is intended for research and analytical applications. ML-SI3 is a mixture of cis/trans ML-SI3 (HY-139426A), which is a TRPML1/2 channel inhibitor with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 also inhibits lysosomal calcium efflux and blocks downstream TRPML1-mediated autophagy. The cis/trans ML-SI3 (HY-139426A) components of ML-SI3 are TRPML2 activators with EC50s of 3.3 μM and 9.4 μM, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 891016-02-7
  • Formula: C23H31N3O3S
  • Molecular Weight:429.58
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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