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Cat. No.: HY-W701876

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Monocyclohexyl phthalate

Name: Monocyclohexyl phthalate
Brand: MedChemExpress
SKU: HY-W701876
Price: 70.00 USD
Availability: InStock
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Monocyclohexyl phthalate is a phthalate metabolite and a competitive UGT1A9 inhibitor with an IC₅₀ of 3.29 μM and a K_i of 0.09 μM. Monocyclohexyl phthalate can be used in research on impaired sperm quality and birth weight.

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CAS No.: 7517-36-4
Formule: C₁₄H₁₆O₄
Masse moléculaire:248.28

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Monocyclohexyl phthalate Chemical Structure

CAS No.: 7517-36-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

IC₅₀ & Target

^[1]

UGT1A9

3.29 μM (IC₅₀)

In Vitro

Monocyclohexyl phthalate (0-100 μM; 30 min) competitively inhibits recombinant human UGT1A9-catalyzed 4-MU glucuronidation with an IC₅₀ of 3.29 μM and a K_i of 0.09 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 7517-36-4
Masse moléculaire 248.28
Formule C₁₄H₁₆O₄
SMILES

O=C(O)C=1C=CC=CC1C(=O)OC2CCCCC2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Du Z, et al. Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters. Chemosphere. 2018 Apr;197:7-13. [Content Brief]

[2]. Vrachnis N, et al. Phthalates and fetal growth velocity: tracking down the suspected links. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2022 Dec;35(25):4985-4993.

[3]. Duty SM, et al. The relationship between environmental exposures to phthalates and DNA damage in human sperm using the neutral comet assay. Environmental health perspectives. 2003 Jul;111(9):1164-9.

[4]. Duty SM, et al. Phthalate exposure and human semen parameters. Epidemiology (Cambridge, Mass.). 2003 May;14(3):269-77.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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