Perrimustine
Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia.
For research use only. We do not sell to patients.
- CAS No.: 96413-13-7
- Formula: C6H12ClN3O3S
- Molecular Weight:241.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 96413-13-7
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Molecular Weight 241.70
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Formula C6H12ClN3O3S
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SMILES
CS(CCNC(N(N=O)CCCl)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kim-Triana B, et al. Phase I trial of Perrimustine, a new cysteamine (2-chloroethyl) nitrosourea: an intrapatient escalation scheme. Anticancer Drugs. 1992 Jun;3(3):225-31. [Content Brief]
[2]. Godeneche D, et al. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells. Cancer Res. 1990 Sep 15;50(18):5898-903. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)