N-Methyldopamine hydrochloride
Based on 1 publication(s) in Google Scholar
N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research.
For research use only. We do not sell to patients.
- Purity: 99.12%
- CAS No.: 62-32-8
- Formula: C9H14ClNO2
- Molecular Weight:203.67
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) N-Methyldopamine hydrochloride
MoreAll Dopamine Receptor Isoforms
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Biological Activity
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D1 Receptor |
N-Methyldopamine hydrochloride shows highly improved surface coating properties, and exhibits an accelerated coating rate. N-Methyldopamine hydrochloride coating makes solid surface cell adhesion possible, and postfunctionalization of the coating is also possible[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 62-32-8
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Appearance Solid
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Molecular Weight 203.67
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Formula C9H14ClNO2
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Color Light brown to gray
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SMILES
CNCCC1=CC(O)=C(O)C=C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Pharmacol Exp Ther
N-Methyldopamine and ibopamine can prevent chemically-induced oxidative ferroptosis in vitro and in vivo. [Abstract]2025 Jul;392(7):103620. PMID: 40570548
Solvent & Solubility
H2O : ≥ 100 mg/mL (490.99 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Kim Y, et al. Effect of N-Methylation on Dopamine Surface Chemistry. Langmuir. 2022 May 24;38(20):6404-6410. [Content Brief]
[2]. Laduron P. N-Methyldopamine (epinine), a precursor of adrenaline in the adrenal medulla. Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:304-. [Content Brief]
[3]. Rajfer SI, et al. Effects of long-term therapy with oral ibopamine on resting hemodynamics and exercise capacity in patients with heart failure: relationship to the generation of N-methyldopamine and to plasma norepinephrine levels. Circulation. 1986 Apr; [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.9099 mL | 24.5495 mL | 49.0990 mL | 122.7476 mL |
| 5 mM | 0.9820 mL | 4.9099 mL | 9.8198 mL | 24.5495 mL | |
| 10 mM | 0.4910 mL | 2.4550 mL | 4.9099 mL | 12.2748 mL | |
| 15 mM | 0.3273 mL | 1.6366 mL | 3.2733 mL | 8.1832 mL | |
| 20 mM | 0.2455 mL | 1.2275 mL | 2.4550 mL | 6.1374 mL | |
| 25 mM | 0.1964 mL | 0.9820 mL | 1.9640 mL | 4.9099 mL | |
| 30 mM | 0.1637 mL | 0.8183 mL | 1.6366 mL | 4.0916 mL | |
| 40 mM | 0.1227 mL | 0.6137 mL | 1.2275 mL | 3.0687 mL | |
| 50 mM | 0.0982 mL | 0.4910 mL | 0.9820 mL | 2.4550 mL | |
| 60 mM | 0.0818 mL | 0.4092 mL | 0.8183 mL | 2.0458 mL | |
| 80 mM | 0.0614 mL | 0.3069 mL | 0.6137 mL | 1.5343 mL | |
| 100 mM | 0.0491 mL | 0.2455 mL | 0.4910 mL | 1.2275 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
N-Methyldopamine hydrochloride Related Classifications
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